The frontman of Welsh rock royalty The Alarm has said his future is "uncertain" after his rare aggressive cancer returned.

Mike Peters, of Dyserth, has appealed to people to become potential stem cell donors.

The 65-year-old musician had to cancel a US tour earlier this year due to his fast-growing lymphoma.

He was given the all-clear in September following experimental therapy at the Christie NHS Foundation Trust in Manchester.

However, he revealed it returned last month.

Mike was first diagnosed with chronic lymphocytic leukaemia (CLL) more than 29 years ago, aged 36.

Earlier this year, medics diagnosed him with Richter's syndrome, where CLL changes into a much more aggressive lymphoma.

He is now on a chemotherapy regime, with a view to starting CAR-T therapy.

This is a complex and specialist type of immunotherapy.

MORE: The Alarm's Mike Peters performs every night of week in Dyserth

Mike said: "I was supposed to be preparing for a stem cell transplant now, exactly 29 years since I was first told I had the disease.

"Unfortunately, Richter's syndrome has aggressively broken down my hard-earned remission and denied me the opportunity to have this potentially life-saving procedure."

Mike established the Love Hope Strength Foundation in 2006 with his wife Jules.

They have two sons, aged 17 and 20, and the family run The Red pub in Mike's hometown of Dyserth.

Mike delivered the opening speech at the World Cancer Congress 2024 in Geneva in September.

Now the foundation has launched a new campaign, One in a Million, to double the number of people signed up as potential stem cell donors, having already encouraged 250,000 people to register.

Mike said: "The future is uncertain, but I still have many options and as I navigate those, I want to make sure I help other blood cancer sufferers like me."

His wife Jules said: "Although this latest set-back has been a devastating blow for our family, it affords us more time to find the best life-saving match for Mike."

Michael Gallagher, from the blood cancer charity DKMS which works in partnership with the foundation, that today only 60 per cent of patients will find a matching stem cell donor.

Mike Peters statement on November 12 to launch the One in a Million campaign:

“I may be living with a rare and aggressive lymphoma, and need a stem cell transplant, but I know I’m lucky. I have my beautiful family, I live in an incredible part of the world, I have my music and all that comes with it.

"I’m also exceptionally lucky because I’m able to access the very best medical treatment and care, and because it looks highly likely that a matching stem cell donor will be found for me. Only 30% of people will have a matching stem cell donor within their own family, which means the vast majority of people will need an unrelated stem cell donor.

"A complete stranger will likely provide a potentially life saving stem cell donation for me. My donor will be my one in a million, my chance of survival.

"Currently, only 60% of patients will find a matching stem cell donor, making the need for new donors critical. Could you register to become a potential blood stem cell donor, and be someone’s one in a million?

"My wife Jules and I have got to know others who like me need that second chance of life, and we want to do more. Through the charity we established together almost two decades ago, Love Hope Strength, we are launching the One in a Million campaign in partnership with
DKMS to register more people to become blood stem cell donors.

"Think about your one in a million. Your partner, your child, parent, or your best friend. Imagine if they need a stem cell donation.

"It’s easy to get registered to be a potential stem cell donor. You can order a swab kit online, and it takes less than 10 minutes.

"Do something great today. Rally everyone you know to get on the list to potentially save a life now.”